- Dactyloptena Jordan & Richardson 1908
- Dallina Beecher 1893
- Dallinella Thomson 1915
- Dallithyris Muir-Wood 1959
- Damalinia Mjöberg 1910
- Damaster Kollar 1836
- Danio Hamilton 1822
- Daphniphyllum Blume
- Darcythompsonia Scott T. 1906
- Dardanus Paulson 1875
- Darumamyzon Ogawa & Matsuzaki 2015
- Darwinula Brady & Robertson in Jones 1885
- Dascyllus Cuvier 1829
- Dasyatis Rafinesque 1810
- Dasybranchus Grube 1850
- Dasycottu T.H. Bean 1890
- Daylithos Salazar-Vallejo 2012
- Decametra A.H. Clark 1911
- Decapterus Bleeker 1851
- Decorifer Iredale 1937
- Decorihastula Oyama 1961
- Degeeriella Neumann 1906
- Delias Hübner 1819
- Delphinus Linnaeus 1758
- Deltocyathoides Yabe & Eguchi 1932
- Demetrias Bonelli 1810
- Dendrobaena Eisen 1874
- Dendrochirus Swainson 1839
- Dendrocopos Koch 1816
- Dendrodoa MacLeay 1824
- Dendropanax Decaisne & J.E. Planchon 1854
- Dendrophyllia de Blainville 1830
- Dentex Cuvier 1814
- Dentostomella Schulz & Krepkogorskaja 1932
- Deomys Thomas 1888
- Dermatolepis Gill 1861
- Dermoergasilus Ho & Do 1982
- Deschampsia Beauvois
- Deshayesiella Carpenter in Dall 1879
- Desmarestia Lamouroux 1813
- Desmatiderma Topsent 1928
- Desportesius Chabaud & Campana 1949
- Dettopsomyia Lamb 1914
- Dexistes Jordan & Starks 1904
- Diacavolinia van der Spoel 1987
- Diacyclops Kiefer 1927
- Diadema Humphreys 1797
- Diagramma Oken 1817
- Dianthus Linné
- Diaphus C.H. Eigenmann & R.S. Eigenmann 1890
- Diaschiza Gosse 1886
- Diastylis Say 1818
- Dichaetophora Duda 1940
- Dicheirotrichus Jacquelin du Val 1857
- Dichopsammia Song 1994
- Dicranoncus Chaudoir 1850
- Dictyocaulus Railliet & Henry 1907
- Dictyopteris J.V. Lamouroux 1809
- Dictyosoma Temminck & Schlegel 1845
- Dicyphus Fieber 1858
- Diestothyris Thomson 1916
- Dietta Sharp 1876
- Diffalaba Iredale 1936
- Digitaria Haller
- Diglyphus Walker 1844
- Dimerosaccus Shimazu 1980
- Dinemoleus Cressey & Boyle 1978
- Dinera Robineau-Desvoidy 1830
- Dineutus Macleay 1825
- Dioctophyme Collet-Meygret 1802
- Diodon Linnaeus 1758
- Diogenes Dana 1851
- Dipetalonema Diesing 1861
- Diplazon Nees 1819
- Diploastrea Matthai 1914
- Diplocheila Brulle 1834
- Diplolepis Geoffrey 1762
- Diplommatina Benson 1849
- Diplonychus Laporte 1833
- Diploprion Cuvier 1828
- Diplothrix Thomas 1916
- Diplotriaena Railliet & Henry 1909
- Diplous Motschulsky 1850
- Diprion Schrank 1802
- Dipsastraea Blainville 1830
- Dipterygonotus Bleeker 1849
- Dipturus Rafinesque 1810
- Dipus Zimmermann 1780
- Dipylidium Leuckart 1863
- Dirhinus Dalman 1818
- Dirofilaria Railliet & Henry 1911
- Dischissus Bates 1873
- Discina Lamarck 1819
- Discinisca Dall 1871
- Discoconulus Reinhardt 1883
- Discothyrea Roger 1863
- Discradisca Stenzel 1964
- Dissomphalus Ashmead 1893
- Dissotrocha Bryce 1910
- Distigma Ehrenberg 1831
- Distylium Siebold & Zuccarini 1841
- Ditrema Temminck & Schlegel 1844
- Diurella Bory de St. Vincent 1824
- Dodecaceria Örsted 1843
- Doederleinia Steindachner 1883
- Dolabella Lamarck 1801
- Dolichoctis Schmidt-Gobel 1846
- Dolichoderus Lund 1831
- Dolichozygus Cooper 1983
- Donax Linnaeus 1758
- Dorcus MacLeay 1819
- Dorichus Bonelli 1810
- Dorometra Clark 1917
- Dorvillea Parfitt 1866
- Dorytomus Germar 1817
- Dosinia Scopoli 1777
- Doubledaya White 1850
- Draschia Chitwood & Wehr 1934
- Drepane Cuvier & Valenciennes 1831
- Drombus Jordan & Seale 1905
- Dromius Bonelli 1810
- Drosophila Fallén 1823
- Drupella Thiele 1925
- Dryocosmus Giraud 1859
- Dryomys Thomas 1906
- Dymecodon True 1886
- Dynamena Lamouroux 1812
- Dynoides Barnard 1914
- Dyobelba Norton 1978
- Dyscolia Fischer & Oehlert 1890
- Dysedrosia Cooper 1983